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Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Mesa

  • Total vacation rentals

    Explore 160 vacation rentals in Mesa

  • Nightly prices starting at

    Mesa vacation rentals start at $42 CAD per night before taxes and fees

  • Verified guest reviews

    Over 14,330 verified reviews to help you choose

  • Family-friendly vacation rentals

    30 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    80 properties have a dedicated workspace

  • Wifi availability

    160 of Mesa vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesa rentals

  • 4.9 Average rating

    Mesa stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Mesa’s top spots, include Golfland Sunsplash, Sloan Park, and Hohokam Stadium

Top-rated guesthouses in Mesa

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

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Guest favourite
A bright guesthouse features floor-to-ceiling windows that provide views of the surrounding landscaping. A spacious bed is positioned adjacent to a seating area and a TV. A decorative area rug complements the modern furnishings, creating a comfortable atmosphere.
Guesthouse in Camelback East
4.97 out of 5 average rating, 818 reviews

Resort-living in private Studio @ Villa Paradiso

* Private, bright guesthouse immersed in a peaceful oasis of lush landscaping. The guesthouse is right in front of our swimming pool. * Fully remodeled: Kitchen, TV, Wifi, Nespresso & more. * Central location: 10 mins from Old Town Scottsdale, ASU, Sky Harbor Airport, Spring Training & more. Check out my profile for two Luxury B&B suite listings in the main house. Private bedroom & bath, full access to living areas + breakfast. Ask about photoshoots or events across the various property areas.

Top guest favourite
Guesthouse in Mesa
4.97 out of 5 average rating, 208 reviews

Entire Suite: Private and Cozy Clark House Casita

Trade the sterile hotel vibe and feel right at home by staying at our quaint and unique historic casita. Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

Top guest favourite
A private room features a spacious bed with layered bedding, complemented by two decorative pillows. A small dining table with two chairs sits in the corner. Large windows with wooden shutters frame a view of greenery outside, and landscape artwork adorns the wall.
Guesthouse in Chandler
4.98 out of 5 average rating, 126 reviews

Cozy Casita with kitchenette

Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Top guest favourite
Guesthouse in Paradise Valley Village
4.99 out of 5 average rating, 143 reviews

Urban Cabin - A unique Retreat

Escape to this one-of-a-kind cedar cabin, offering a private sanctuary in the heart of the city. Thoughtfully designed w/a modern edge, it features expansive windows flooding interior w/natural light yet maintaining a cozy, secluded feel. Outside, a private yard, where you'll find an antique clawfoot tub/shower, perfect for unwinding under the open sky. Inside, industrial elements blend seamlessly w/warm cedar tones, creating an inviting atmosphere ideal for both relaxation & inspiration.

Top guest favourite
Guesthouse in Chandler
4.92 out of 5 average rating, 189 reviews

Historic Firehouse Downtown Chandler Large shower

Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

Top guest favourite
A bright and airy studio space features a comfortable bed with crisp white bedding and a cozy sitting area with a plush sofa. Natural light fills the room through the window, and a small bedside table with a lamp adds a touch of warmth.
Guesthouse in Mesa
4.98 out of 5 average rating, 310 reviews

Private, Convenient Studio Apartment

Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Top guest favourite
A spacious bedroom is highlighted by natural light from a door leading outside. The room features a queen size bed covered with a blue striped comforter, flanked by two bedside tables with lamps. Framed artwork adorns the walls, adding character to the space.
Guesthouse in Mesa
4.94 out of 5 average rating, 321 reviews

Cozy, Private Mid-Century Casita

Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Guest favourite
A bright living area is presented with a comfortable sectional sofa and accent chairs in various shades of grey and teal. A television is positioned on a stylish media console, while a decorative area rug adds color beneath a coffee table. Natural light filters through the window.
Guesthouse in East Mesa
4.93 out of 5 average rating, 204 reviews

Detached Guesthouse | Full Kitchen & Parking

Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Top guest favourite
Guesthouse in East Mesa
4.89 out of 5 average rating, 364 reviews

Casita/ Heated Pool, Hot Tub, Amazing Amenities

Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Guest favourite
An open-concept studio features a well-lit living area with modern furnishings. A dining table with four chairs is positioned near the kitchen, which includes white cabinets and stainless steel appliances. French doors provide access to the entrance, while a ceiling fan adds comfort.
Guesthouse in East Mesa
4.95 out of 5 average rating, 149 reviews

Private Luxury Guesthouse in Mesa

Relax in this calm, stylish space. This guesthouse is the perfect getaway for couples or solo travelers. + King Bed + Sofa Bed + Firepit + Nespresso Machine + 2 Burner Cooktop + Cocktail Shaker Set + Full-Length Mirror + Comfy Robes + Rain Shower Head + Water Softener + Dedicated Parking + Private Entrance 8 min ➡ Downtown Mesa 10 min ➡ Downtown Gilbert 20 min ➡ Sky Harbor Airport 30 min ➡ Central Phoenix @glade.guesthouse

Top guest favourite
A bright and airy living space features a comfortable light-colored couch adorned with decorative pillows and a soft throw. A glass dining table for two is set beside a window with elegant window treatments, while wall art and decor add a touch of personality.
Guesthouse in Chandler
4.97 out of 5 average rating, 416 reviews

Private-Detached Guesthouse & Zen Courtyard

Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Top guest favourite
A welcoming guest house is presented with a blend of white siding and natural stone accents, framed by lush greenery. A pathway leads to the entrance, flanked by well-maintained gardens. An American flag is displayed, contributing to the property’s inviting exterior.
Guesthouse in Mesa
4.95 out of 5 average rating, 182 reviews

The White Barn @ Freedom Farms

Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

Popular amenities for Mesa guesthouses

Destinations to explore