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Apartment vacation rentals in Panama City

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in Panama City

  • Total vacation rentals

    Explore 3,150 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at $14 CAD per night before taxes and fees

  • Verified guest reviews

    Over 97,220 verified reviews to help you choose

  • Family-friendly vacation rentals

    1,010 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 1,180 rentals that welcome pets

  • Vacation rentals with a pool

    2,170 properties feature pools

  • Rentals with dedicated workspaces

    2,060 properties have a dedicated workspace

  • Wifi availability

    3,090 of Panama City vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated apartment rentals in Panama City

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favourite
A historic building with a prominent tower features elegant architecture, complemented by lush greenery in the foreground. Nearby palms and flowering trees create a serene environment, while the sky offers soft blue tones, enhancing the overall ambiance of the vibrant Casco Antiguo area.
Apartment in San Felipe
4.81 out of 5 average rating, 139 reviews

Best Location – Fancy Apartment in Casco Viejo

Experience absolute luxury in our fully remodeled loft, with access to a spectacular 360° rooftop terrace, where you'll enjoy breathtaking views of the city and skyline. The building also features an elevator for your convenience. Located right in front of a vibrant plaza with renowned restaurants, the location is truly unbeatable, and security in the area is excellent. Relax in the rooftop, enjoy sunset views from the terrace, and experience the unique charm of Panama’s historic Casco Antiguo

Superhost
Apartment in Panamá
4.92 out of 5 average rating, 168 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top guest favourite
An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.
Apartment in Panama City
4.92 out of 5 average rating, 133 reviews

Impresionante con vista al mar y a Panamá city

Vive una experiencia única, apartamento moderno y con estilo propio, donde cada amanecer y atardecer se convierte en un espectáculo. Disfruta de impresionantes vistas a la ciudad de Panamá, la bahía y el Casco Antiguo desde la comodidad de tu alojamiento. Ubicación Inmejorable Situado a solo 5 minutos del encantador Casco Viejo y del famoso mercado de mariscos, y a 10 minutos de zona bancaria. Además, contarás con una estación de metro y varias paradas de autobús a solo unos pasos del edificio

Guest favourite
Apartment in San Felipe
4.96 out of 5 average rating, 258 reviews

En el corazón de Casco, remodelado y con parking

Escápate y descubre casco antiguo en este remodelado , cómodo y céntrico alojamiento en el corazón de Casco Viejo. Nuestra ubicación es lo mejor, te hará regresar. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, cama king europea, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar -Cocina full equipada

Top guest favourite
Apartment in San Felipe
4.98 out of 5 average rating, 127 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Superhost
Apartment in San Felipe
4.77 out of 5 average rating, 198 reviews

Apartamento tipo estudio en el corazón de Casco

¡Bienvenidos a Casa Pérez, tu refugio en el corazón del Casco Viejo! Disfruta de una ubicación privilegiada y de las mejores vistas desde un espectacular balcón privado frente a la plaza más emblemática del Casco. Ideal para 3 personas, este acogedor y luminoso apartamento de un dormitorio incluye Wifi, aire acondicionado, sala, comedor, cocina equipada, lavadora y elevador para tu comodidad. Disfruta de una estadía inolvidable en un ambiente cálido y completamente equipado.

Guest favourite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Apartment in Bella Vista
4.8 out of 5 average rating, 139 reviews

Ocean View Apt in Panama, Yoo&Arts

Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Top guest favourite
Apartment in San Felipe
4.97 out of 5 average rating, 36 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Guest favourite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in San Felipe
4.91 out of 5 average rating, 125 reviews

La mejor vista del Casco Antiguo

¡Bienvenidos a este encantador alojamiento situado en el corazón del Casco Viejo, ubicado en el tercer piso frente a una de las plazas más emblemáticas de Panamá, la Plaza Catedral! Gracias a su privilegiada ubicación, disfrutarás de una vista única a la plaza y a la imponente Iglesia Catedral. Justo en esta animada plaza, tendrás a tu disposición una amplia variedad de restaurantes y tiendas donde podrás adquirir recuerdos de este maravilloso viaje.

Guest favourite
Apartment in Panamá
4.89 out of 5 average rating, 102 reviews

Moderno, céntrico y cómodo (104)

Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

Guest favourite
Apartment in Bella Vista
4.93 out of 5 average rating, 133 reviews

Espectaculares vistas piscina y ubicación ideal

Disfruta una experiencia inolvidable en una ubicación privilegiada de Ciudad de Panama. Despierta con impresionantes vistas de los edificios, el mar. Relajate en la piscina o el rooftop y siéntete como en casa gracias a nuestra hospitalidad. A pocos minutos del Casco Antiguo, Cinta Costera, Metro, Restaurantes, bares y centros comerciales, Albrook Mall, Multiplaza Mall, Soho Mall. Ideal para vacaciones o viajes de negocios.

Guest favourite
Apartment in San Francisco
4.98 out of 5 average rating, 160 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

Popular amenities for Panama City apartment rentals

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